PRENATAL DIAGNOSIS OF WOLF-HIRSCHHORN SYNDROME CONFIRMED BY COMPARATIVE GENOMIC HYBRIDIZATION ARRAY: REPORT OF TWO CASES AND REVIEW OF THE LITERATURE

Prenatal diagnosis of Wolf-Hirschhorn syndrome confirmed by comparative genomic hybridization array: report of two cases and review of the literature

Abstract Wolf-Hirschhorn syndrome (WHS) is a well known genetic condition caused by a partial deletion of the short arm of chromosome 4.The great variability in the extent of the 4p deletion and the possible contribution of additional genetic rearrangements lead to a wide spectrum of clinical manifestations.The majority of the reports of prenatally

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